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1

Molecular Pharmacology and Neurobiology of Rapid-Acting Antidepressants

Gould, Todd D., Zarate Jr., Carlos A., Thompson, Scott M.

Journal:

Annual Review of Pharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2019

2

Synaptic Potentiation Is Critical for Rapid Antidepressant Response to Ketamine in Treatment-Resistant Major Depression

Brian R. Cornwell, Giacomo Salvadore, Maura Furey, Craig A. Marquardt, Nancy E. Brutsche, Christian Grillon, Carlos A. Zarate Jr.

Journal:

Biological Psychiatry

Année:

2012

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2012

3

First-episode schizophreniform disorder: comparisons with first-episode schizophrenia

Carlos A. Zarate Jr., Mauricio Tohen, Michelle L. Land

Journal:

Schizophrenia Research

Année:

2000

Langue:

english

Fichier:

PDF, 70 KB

english, 2000

4

Neural Circuitry and Neuroplasticity in Mood Disorders: Insights for Novel Therapeutic Targets

Paul J. Carlson, Jaskaran B. Singh, Carlos A. Zarate Jr, Wayne C. Drevets, Husseini K. Manji

Journal:

Neurotherapeutics

Année:

2006

Langue:

english

Fichier:

PDF, 657 KB

english, 2006

5

Pharmacological treatment of psychiatric comorbidity in bipolar disorder: a review of controlled trials

Jaskaran B Singh, Carlos A Zarate Jr

Journal:

Bipolar Disorders

Année:

2006

Langue:

english

Fichier:

PDF, 619 KB

english, 2006

6

Efficacy of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania: a pilot study

Carlos A Zarate Jr, Jaskaran B Singh, Paul J Carlson, Jorge Quiroz, Libby Jolkovsky, David A Luckenbaugh, Husseini K Manji

Journal:

Bipolar Disorders

Année:

2007

Langue:

english

Fichier:

PDF, 548 KB

english, 2007

7

Hot and cold cognition in unmedicated depressed subjects with bipolar disorder

Jonathan P Roiser, Dara M Cannon, Shilpa K Gandhi, Joana Taylor Tavares, Kristine Erickson, Suzanne Wood, Jacqueline M Klaver, Luke Clark, Carlos A Zarate Jr, Barbara J Sahakian, Wayne C Drevets

Journal:

Bipolar Disorders

Année:

2009

Langue:

english

Fichier:

PDF, 184 KB

english, 2009

8

The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis

Rodrigo Machado-Vieira, Husseini K Manji, Carlos A Zarate Jr

Journal:

Bipolar Disorders

Année:

2009

Langue:

english

Fichier:

PDF, 228 KB

english, 2009

9

Regulation of Cellular Plasticity Cascades in the Pathophysiology and Treatment of Mood Disorders : Role of the Glutamatergic System

CARLOS A. ZARATE JR., JING DU, JORGE QUIROZ, NEIL A. GRAY, KIRK D. DENICOFF, JASKARAN SINGH, DENNIS S. CHARNEY, HUSSEINI K. MANJI

Journal:

Annals of the New York Academy of Sciences

Année:

2003

Fichier:

PDF, 325 KB

2003

10

Is there a relationship between clozapine and obsessive-compulsive disorder?: A retrospective chart review

S Nassir Ghaemi, Carlos A Zarate Jr., Anand P Popli, Srinivasan S Pillay, Jonathan O Cole

Journal:

Comprehensive Psychiatry

Année:

1995

Langue:

english

Fichier:

PDF, 326 KB

english, 1995

11

Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression

Husseini K Manji, Jorge A Quiroz, Jonathan Sporn, Jennifer L Payne, Kirk Denicoff, Neil A. Gray, Carlos A Zarate Jr., Dennis S Charney

Journal:

Biological Psychiatry

Année:

2003

Langue:

english

Fichier:

PDF, 607 KB

english, 2003

12

Pramipexole for bipolar II depression: a placebo-controlled proof of concept study

Carlos A Zarate Jr., Jennifer L Payne, Jaskaran Singh, Jorge A Quiroz, David A Luckenbaugh, Kirk D Denicoff, Dennis S Charney, Husseini K Manji

Journal:

Biological Psychiatry

Année:

2004

Langue:

english

Fichier:

PDF, 143 KB

english, 2004

13

Targeting the Glutamatergic System to Treat Major Depressive Disorder

Daniel C. Mathews, Ioline D. Henter, Dr Carlos A. Zarate Jr

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 274 KB

english, 2012

14

Proof of concept trials in bipolar disorder and major depressive disorder: a translational perspective in the search for improved treatments

Rodrigo Machado-Vieira, Carlos A. Zarate Jr.

Journal:

Depression and Anxiety

Année:

2011

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2011

15

Combination treatment in bipolar disorder: a review of controlled trials

Carlos A. Zarate Jr., Jorge A. Quiroz

Journal:

Bipolar Disorders

Année:

2003

Langue:

english

Fichier:

PDF, 121 KB

english, 2003

16

A comparison of cognitive functioning in medicated and unmedicated subjects with bipolar depression

M Kathleen Holmes, Kristine Erickson, David A Luckenbaugh, Wayne C Drevets, Earle E Bain, Dara M Cannon, Joseph Snow, Barbara J Sahakian, Husseini K Manji, Carlos A Zarate Jr

Journal:

Bipolar Disorders

Année:

2008

Langue:

english

Fichier:

PDF, 177 KB

english, 2008

17

Histone Deacetylases and Mood Disorders: Epigenetic Programming in Gene-Environment Interactions

Rodrigo Machado-Vieira, Lobna Ibrahim, Carlos A. Zarate, Jr.

Journal:

CNS Neuroscience & Therapeutics

Année:

2011

Langue:

english

Fichier:

PDF, 325 KB

english, 2011

18

Automated subcortical segmentation using FIRST: Test–retest reliability, interscanner reliability, and comparison to manual segmentation

Allison C. Nugent, David A. Luckenbaugh, Suzanne E. Wood, Wendy Bogers, Carlos A. Zarate Jr., Wayne C Drevets

Journal:

Human Brain Mapping

Année:

2012

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2012

19

Bipolar disorder: candidate drug targets

Carlos A. Zarate Jr, Husseini K. Manji

Journal:

Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 210 KB

english, 2008

20

Perception of facial emotion in adults with bipolar or unipolar depression and controls

Kathryn L. Schaefer, Jacqueline Baumann, Brendan A. Rich, David A. Luckenbaugh, Carlos A. Zarate Jr.

Journal:

Journal of Psychiatric Research

Année:

2010

Langue:

english

Fichier:

PDF, 201 KB

english, 2010

21

Novel glutamatergic agents for major depressive disorder and bipolar disorder

Rodrigo Machado-Vieira, Lobna Ibrahim, Ioline D. Henter, Carlos A. Zarate Jr.

Journal:

Pharmacology Biochemistry and Behavior

Année:

2012

Langue:

english

Fichier:

PDF, 303 KB

english, 2012

22

Ketamine and the next generation of antidepressants with a rapid onset of action

Rodrigo Machado-Vieira, Giacomo Salvadore, Nancy DiazGranados, Carlos A. Zarate Jr.

Journal:

Pharmacology & Therapeutics

Année:

2009

Langue:

english

Fichier:

PDF, 386 KB

english, 2009

23

Shifts in hospital diagnostic frequencies: bipolar disorder subtypes, 1981–1993

Carlos A Zarate, Jr, Mauricio Tohen, German Baraibar, Silvina B Zarate, Ross J Baldessarini

Journal:

Journal of Affective Disorders

Année:

1997

Langue:

english

Fichier:

PDF, 165 KB

english, 1997

24

Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression

Xiaochen Zhao, Swarajya Lakshmi Vattem Venkata, Ruin Moaddel, Dave A. Luckenbaugh, Nancy E. Brutsche, Lobna Ibrahim, Carlos A. Zarate Jr, Donald E. Mager, Irving W. Wainer

Journal:

British Journal of Clinical Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2012

25

Rapid antidepressant changes with sleep deprivation in major depressive disorder are associated with changes in vascular endothelial growth factor (VEGF): A pilot study

Lobna Ibrahim, Wallace Duncan, David A. Luckenbaugh, Peixiong Yuan, Rodrigo Machado-Vieira, Carlos A. Zarate Jr.

Journal:

Brain Research Bulletin

Année:

2011

Langue:

english

Fichier:

PDF, 311 KB

english, 2011

26

The Role of AMPA receptor modulation in the treatment of neuropsychiatric diseases

Carlos A. Zarate Jr., Husseini K. Manji

Journal:

Experimental Neurology

Année:

2008

Langue:

english

Fichier:

PDF, 124 KB

english, 2008

27

Association between subcortical volumes and verbal memory in unmedicated depressed patients and healthy controls

Arlener D. Turner, Maura L. Furey, Wayne C. Drevets, Carlos Zarate Jr, Allison C. Nugent

Journal:

Neuropsychologia

Année:

2012

Langue:

english

Fichier:

PDF, 409 KB

english, 2012

28

Increased uric acid levels in drug-naïve subjects with bipolar disorder during a first manic episode

Giacomo Salvadore, Carlos I. Viale, David A. Luckenbaugh, Vanessa C. Zanatto, Luiz V. Portela, Diogo O. Souza, Carlos A. Zarate Jr., Rodrigo Machado-Vieira

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Année:

2010

Langue:

english

Fichier:

PDF, 174 KB

english, 2010

29

Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression

Lobna Ibrahim, Nancy Diazgranados, David A. Luckenbaugh, Rodrigo Machado-Vieira, Jacqueline Baumann, Alan G. Mallinger, Carlos A. Zarate Jr.

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Année:

2011

Langue:

english

Fichier:

PDF, 307 KB

english, 2011

30

Baseline mood-state measures as predictors of antidepressant response to scopolamine

Maura L. Furey, Allison C. Nugent, Andrew M. Speer, David A. Luckenbaugh, Elana M. Hoffman, Erica Frankel, Wayne C. Drevets, Carlos A. Zarate Jr.

Journal:

Psychiatry Research

Année:

2012

Langue:

english

Fichier:

PDF, 327 KB

english, 2012

31

Family history of alcohol dependence and antidepressant response to an N-methyl-d-aspartate antagonist in bipolar depression

David A Luckenbaugh, Lobna Ibrahim, Nancy Brutsche, Jose Franco-Chaves, Daniel Mathews, Craig A Marquardt, Christy Cassarly, Carlos A Zarate Jr

Journal:

Bipolar Disorders

Année:

2012

Langue:

english

Fichier:

PDF, 288 KB

english, 2012

32

A selective neurokinin-1 receptor antagonist in chronic PTSD: A randomized, double-blind, placebo-controlled, proof-of-concept trial

Sanjay J. Mathew, Meena Vythilingam, James W. Murrough, Carlos A. Zarate Jr., Adriana Feder, David A. Luckenbaugh, Becky Kinkead, Michael K. Parides, David G. Trist, Massimo S. Bani, Paolo U. Bettica,

Journal:

European Neuropsychopharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 499 KB

english, 2011

33

Early improvement of psychotic symptoms with lithium monotherapy as a predictor of later response in mania

Rafael T. de Sousa, Joao V. Busnello, Orestes V. Forlenza, Marcus V. Zanetti, Marcio G. Soeiro-de-Souza, Martinus T. van de Bilt, Ricardo A. Moreno, Carlos A. Zarate Jr., Wagner F. Gattaz, Rodrigo Mac

Journal:

Journal of Psychiatric Research

Année:

2012

Langue:

english

Fichier:

PDF, 221 KB

english, 2012

34

An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression

Carlos A. Zarate Jr., Jorge A. Quiroz, Jaskaran B. Singh, Kirk D. Denicoff, Georgette De Jesus, David A. Luckenbaugh, Dennis S. Charney, Husseini K. Manji

Journal:

Biological Psychiatry

Année:

2005

Langue:

english

Fichier:

PDF, 95 KB

english, 2005

35

Cellular Plasticity Cascades: Targets for the Development of Novel Therapeutics for Bipolar Disorder

Carlos A. Zarate Jr, Jaskaran Singh, Husseini K. Manji

Journal:

Biological Psychiatry

Année:

2006

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2006

36

Regional Cerebral Glucose Metabolic Abnormalities in Bipolar II Depression

Linda Mah, Carlos A. Zarate Jr, Jaskaran Singh, Yu-Fei Duan, David A. Luckenbaugh, Husseini K. Manji, Wayne C. Drevets

Journal:

Biological Psychiatry

Année:

2007

Langue:

english

Fichier:

PDF, 540 KB

english, 2007

37

Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

Sungho Maeng, Carlos A. Zarate Jr, Jing Du, Robert J. Schloesser, Joseph McCammon, Guang Chen, Husseini K. Manji

Journal:

Biological Psychiatry

Année:

2008

Langue:

english

Fichier:

PDF, 226 KB

english, 2008

38

Increased Anterior Cingulate Cortical Activity in Response to Fearful Faces: A Neurophysiological Biomarker that Predicts Rapid Antidepressant Response to Ketamine

Giacomo Salvadore, Brian R. Cornwell, Veronica Colon-Rosario, Richard Coppola, Christian Grillon, Carlos A. Zarate Jr., Husseini K. Manji

Journal:

Biological Psychiatry

Année:

2009

Langue:

english

Fichier:

PDF, 553 KB

english, 2009

39

Family History of Alcohol Dependence and Initial Antidepressant Response to an N-methyl-D-aspartate Antagonist

Laura E. Phelps, Nancy Brutsche, Jazmin R. Moral, David A. Luckenbaugh, Husseini K. Manji, Carlos A. Zarate Jr.

Journal:

Biological Psychiatry

Année:

2009

Langue:

english

Fichier:

PDF, 260 KB

english, 2009

40

Bcl-2 Polymorphism Influences Gray Matter Volume in the Ventral Striatum in Healthy Humans

Giacomo Salvadore, Allison C. Nugent, Guang Chen, Nirmala Akula, Peixiong Yuan, Dara M. Cannon, Carlos A. Zarate Jr, Francis J. McMahon, Husseini K. Manji, Wayne C. Drevets

Journal:

Biological Psychiatry

Année:

2009

Langue:

english

Fichier:

PDF, 327 KB

english, 2009

41

Magnetic Resonance Spectroscopy Studies of the Glutamatergic System in Mood Disorders: A Pathway to Diagnosis, Novel Therapeutics, and Personalized Medicine?

Giacomo Salvadore, Carlos A. Zarate Jr.

Journal:

Biological Psychiatry

Année:

2010

Langue:

english

Fichier:

PDF, 497 KB

english, 2010

42

Habenula Volume in Bipolar Disorder and Major Depressive Disorder: A High-Resolution Magnetic Resonance Imaging Study

Jonathan B. Savitz, Allison C. Nugent, Wendy Bogers, Jonathan P. Roiser, Earle E. Bain, Alexander Neumeister, Carlos A. Zarate Jr., Husseini K. Manji, Dara M. Cannon, Sean Marrett, Fritz Henn, Dennis

Journal:

Biological Psychiatry

Année:

2011

Langue:

english

Fichier:

PDF, 819 KB

english, 2011

43

The Bcl-2 Gene Polymorphism rs956572AA Increases Inositol 1,4,5-Trisphosphate Receptor–Mediated Endoplasmic Reticulum Calcium Release in Subjects with Bipolar Disorder

Rodrigo Machado-Vieira, Natalia B. Pivovarova, Ruslan I. Stanika, Peixiong Yuan, Yun Wang, Rulun Zhou, Carlos A. Zarate Jr., Wayne C. Drevets, Christine A. Brantner, Amber Baum, Gonzalo Laje, Francis

Journal:

Biological Psychiatry

Année:

2011

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2011

44

Replication of Ketamine's Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial

Carlos A. Zarate Jr., Nancy E. Brutsche, Lobna Ibrahim, Jose Franco-Chaves, Nancy Diazgranados, Anibal Cravchik, Jessica Selter, Craig A. Marquardt, Victoria Liberty, David A. Luckenbaugh

Journal:

Biological Psychiatry

Année:

2012

Langue:

english

Fichier:

PDF, 962 KB

english, 2012

45

Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Antidepressant Efficacy of Ketamine in Depressed Patients

Gonzalo Laje, Níall Lally, Daniel Mathews, Nancy Brutsche, Anat Chemerinski, Nirmala Akula, Benjamin Kelmendi, Arthur Simen, Francis J. McMahon, Gerard Sanacora, Carlos Zarate Jr.

Journal:

Biological Psychiatry

Année:

2012

Langue:

english

Fichier:

PDF, 102 KB

english, 2012

46

Downregulation of Brain Phosphodiesterase Type IV Measured with 11C-(R)-Rolipram Positron Emission Tomography in Major Depressive Disorder

Masahiro Fujita, Christina S. Hines, Sami S. Zoghbi, Alan G. Mallinger, Leah P. Dickstein, Jeih-San Liow, Yi Zhang, Victor W. Pike, Wayne C. Drevets, Robert B. Innis, Carlos A. Zarate Jr.

Journal:

Biological Psychiatry

Année:

2012

Langue:

english

Fichier:

PDF, 577 KB

english, 2012

47

Relationship of Ketamine's Plasma Metabolites with Response, Diagnosis, and Side Effects in Major Depression

Carlos A. Zarate Jr., Nancy Brutsche, Gonzalo Laje, David A. Luckenbaugh, Swarajya L. Vattem Venkata, Anuradha Ramamoorthy, Ruin Moaddel, Irving W. Wainer

Journal:

Biological Psychiatry

Année:

2012

Langue:

english

Fichier:

PDF, 630 KB

english, 2012

48

Ketamine for Depression: Where Do We Go from Here?

Marije aan het Rot, Carlos A. Zarate Jr., Dennis S. Charney, Sanjay J. Mathew

Journal:

Biological Psychiatry

Année:

2012

Langue:

english

Fichier:

PDF, 399 KB

english, 2012

49

Molecular mechanisms of bipolar disorder

Carlos A. Zarate Jr., Jaskaran B. Singh, Paul J. Carlson, Husseini K. Manji

Journal:

Drug Discovery Today: Disease Mechanisms

Année:

2005

Langue:

english

Fichier:

PDF, 470 KB

english, 2005

50

Enhancing AMPA to NMDA throughput as a convergent mechanism for antidepressant action

Jing Du, Rodrigo Machado-Vieira, Sungho Maeng, Keri Martinowich, Husseini K. Manji, Carlos A. Zarate Jr

Journal:

Drug Discovery Today: Therapeutic Strategies

Année:

2006

Langue:

english

Fichier:

PDF, 752 KB

english, 2006